QotNews Hacker News, Reddit, Lobsters, and Tildes articles rendered in reader mode.
A New Alzheimer’s Drug Reversed Memory Decline in Mice Even After Symptoms Appeared: A new experimental Alzheimer’s compound called FLAV-27 improved memory and reduced disease-like damage in worms and mice.
Genuinely curious how would you test a mouse’s memory, then give it Alzheimer’s to chart its decline then test to see if its memory got better on the medication?
Or is it more like a brain scan where you can see damaged and repaired areas?
Train the mouse on a task, like running a maze for example. Damage memory centers to simulate Alzheimer's. Test it on the maze to confirm it forgot the training. Give it experimental drug. Test it on the maze again.
Random_182f2565 | 26 days ago
Another step closer to mouse immortality
jsmith_92 | 26 days ago
Scientist: do you member?
Mouse: sure do!
More-Dot346 | 26 days ago
Movie elevator pitch: it’s Planet of the Apes meets Ben.
HandshakeOfCO | 26 days ago
It’s crazy to me that they haven’t made a Flowers for Algernon movie yet
More-Dot346 | 26 days ago
Charlie
Slippery_Williams | 26 days ago
Genuinely curious how would you test a mouse’s memory, then give it Alzheimer’s to chart its decline then test to see if its memory got better on the medication?
Or is it more like a brain scan where you can see damaged and repaired areas?
doogihowser | 26 days ago
Train the mouse on a task, like running a maze for example. Damage memory centers to simulate Alzheimer's. Test it on the maze to confirm it forgot the training. Give it experimental drug. Test it on the maze again.
itsnobigthing | 25 days ago
Improving memory - working memory - is not the same thing as returning lost memories. It’s just about capacity to learn and store new information.
CelisForCelery33 | 26 days ago
gcse biology already predicted this
Wonderful-Medium7777 | 26 days ago
I do recall one time that I may have been a mouse, but never a worm if memory serves me.