It's curious to observe that the organs functioned, but then took about a day and a half to begin rejection, so it works as a short bandaid between transplants when nothing better is available. But I am more interested in seeing tests with washed pig organs that had their cells replaced with human cells, those seem to last a lot longer and ought to get perfected.
Getting an actually decent scaffold is one of the biggest hurdles for creating organs.
Ok, but what if I have impure thoughts all day anyway? Would a couple of organs and intestines be sufficient? Or do I need to lard up and go for the full collectible set?
I am somewhat inexperienced in the field, but what you are refering to is like only kwwp the remaining stuctures right? If that is the case, couls they use the recipients own dna and stop the organ from failing completely?
It definitely could, so people's cells have tags on their surface that the immune system uses to recognize whether or not it's a foreign cell, this is why blood type is important when it comes to transfusions. This is also why people need to have their immune system suppressed when they get an organ transplant.
But the concept of seeding an organ with the recipients own cells, that had been proliferated in a bioreactor, has good potential for creating a transplant that doesn't require so much immune suppression and lowers the likelihood of rejection.
I think an even better pathway toward this are organoids, since those are quite literally structures created from the proliferated cells themselves, not relying on a scaffold that came from a different animal.
But we are still early in that, and they are quite small at the moment.
They have used GM organs on patients before. They lived a wee bit longer. On a much sadder note, the pigs died much younger than they should have.
Have you ever heard pigs scream when they are being delivered to the abattoir? They know! They are petrified and traumatised. Murder.
Yes it's sad to dwell on. Do you have an alternative suggestion? Or should we just stop doing healthcare, altogether? When it's your time, it's your time, even if you're a newborn with diabetes. But, hey, at least pigs don't scream. Well, I'm sure they will scream whenever their time comes, but at least we won't hear it?
I read it as they're developing technology to hold people over who are waiting on transplant lists for long periods. Obviously we have a long way to go regarding that
There's been pig organ transplant patients who have survived months, this is the first multiple organ transplant I've heard of. Seems to have been doing well until the inevitable immune response but the amount of preparation and luck it takes for just one succesful kidney xenotransplant is immense so this is very promising.
I have CHF. I’m fairly healthy but know I’m on the “clock” for long term survival. I’m hoping this research concludes with something that can extend my life to a “normal” state. Bring on my replacement pig heart
It’s an interesting test to say the least. I want to read more on how the genetically altered the pig. so far lasting 36 hours would be good in the most desperate of pinches but a lot of things still need to be figured out. We’ll we the continued experiments in the next few years I’m sure
Poor animal. I hate these “experiments in cruelty”. I believe (me, myself I) you are free to choose. Kill a genetically modified animal in order to try and prolong another animal’s life. When I die, I believe I will be reunited with all my pets who have passed. Religious people cannot begin to consider that we are murdering in order to eat. This is why, animals cannot have souls. I am not perfect, those that I failed at the time can and will rebuke me - if they so choose. If your time is up, accept it, don’t sacrifice more life to attempt to prolong yours. Why are you more important? Is their 100 percent consensus on your superior status? Or maybe narcissism?
Colddigger | 9 hours ago
It's curious to observe that the organs functioned, but then took about a day and a half to begin rejection, so it works as a short bandaid between transplants when nothing better is available. But I am more interested in seeing tests with washed pig organs that had their cells replaced with human cells, those seem to last a lot longer and ought to get perfected.
Getting an actually decent scaffold is one of the biggest hurdles for creating organs.
Regurgitator001 | 9 hours ago
So. How many pig donor organs does it take to render oneself pig and not human? I'm asking for a friend. (And for stuff like paying taxes).
Guilty_Perception_35 | 7 hours ago
Pigman of theseus
Eledridan | 6 hours ago
Manbearpig.
Expert-Debate3519 | 8 hours ago
I gutes the brain is the ultimate individual Organ. I know you mean it as a Joke but i Would redifine individuality around the brain :D
HandshakeOfCO | 3 hours ago
It’s true. Only the brainless don’t pay taxes!
Regurgitator001 | 2 hours ago
Ok, but what if I have impure thoughts all day anyway? Would a couple of organs and intestines be sufficient? Or do I need to lard up and go for the full collectible set?
Cut_Lanky | 4 hours ago
Very out of the box thinking, I like it. Work smarter, not harder 🤓
Arthur_Burt_Morgan | 7 hours ago
I am somewhat inexperienced in the field, but what you are refering to is like only kwwp the remaining stuctures right? If that is the case, couls they use the recipients own dna and stop the organ from failing completely?
Colddigger | an hour ago
It definitely could, so people's cells have tags on their surface that the immune system uses to recognize whether or not it's a foreign cell, this is why blood type is important when it comes to transfusions. This is also why people need to have their immune system suppressed when they get an organ transplant. But the concept of seeding an organ with the recipients own cells, that had been proliferated in a bioreactor, has good potential for creating a transplant that doesn't require so much immune suppression and lowers the likelihood of rejection.
I think an even better pathway toward this are organoids, since those are quite literally structures created from the proliferated cells themselves, not relying on a scaffold that came from a different animal. But we are still early in that, and they are quite small at the moment.
LadyZoe1 | 8 hours ago
They have used GM organs on patients before. They lived a wee bit longer. On a much sadder note, the pigs died much younger than they should have.
Have you ever heard pigs scream when they are being delivered to the abattoir? They know! They are petrified and traumatised. Murder.
GrandFleshMelder | 8 hours ago
I mean, we use them as livestock anyway. They might as well help save someone’s life.
Cut_Lanky | 4 hours ago
Yes it's sad to dwell on. Do you have an alternative suggestion? Or should we just stop doing healthcare, altogether? When it's your time, it's your time, even if you're a newborn with diabetes. But, hey, at least pigs don't scream. Well, I'm sure they will scream whenever their time comes, but at least we won't hear it?
Specialist-Yak7209 | 4 hours ago
I guess we should let people waiting for organs just die then
HandshakeOfCO | 3 hours ago
Yes obviously we can’t hurt the wee piggie wiggies, they’re so cuuuuuuute lol 🙄
Call me an immoral troglodyte, but I’d kill a lot more than just a pig if it helped extend the lifespans of the people I love.
HandshakeOfCO | 3 hours ago
Murder by definition applies only to humans. Stop misappropriating words to further your ridiculous cause.
IcySkyDream | 9 hours ago
Do you want ManBearPig?
Because this is how you get ManBearPig.
JackFisherBooks | 4 hours ago
Al Gore is sweating nervously at this news.
camshun7 | 5 hours ago
bladder Runner
blueberrywalrus | 9 hours ago
Three organs getting rejected instead the usual one doesn't seem much more impressive.
I mean, it's great they can do more research with each donor body, but the headline certainly reads as if the transplants were viable.
hydrohorton | 7 hours ago
I read it as they're developing technology to hold people over who are waiting on transplant lists for long periods. Obviously we have a long way to go regarding that
DoomedOrbital | 7 hours ago
There's been pig organ transplant patients who have survived months, this is the first multiple organ transplant I've heard of. Seems to have been doing well until the inevitable immune response but the amount of preparation and luck it takes for just one succesful kidney xenotransplant is immense so this is very promising.
txroller | 4 hours ago
I have CHF. I’m fairly healthy but know I’m on the “clock” for long term survival. I’m hoping this research concludes with something that can extend my life to a “normal” state. Bring on my replacement pig heart
YourDreams2Life | 10 hours ago
Question! If you now have pig organs, does that make you part pig? And if you're part pig now, does that mean it's cannibalism when you eat pork?
wild_crazy_ideas | 8 hours ago
Obviously you’d be at risk for any diseases in the pig but we already cook pork pretty well because of the similarities
Glittering-Lead246 | 4 hours ago
What a thing -- saved by the transplant only to be cooked!
ryohayashi1 | 2 hours ago
Didnt the last pig organ transplant not last and the guy died in less than six months?
FraGough | 10 hours ago
7 out of 10 cannibals said the results were "delicious".
badwolf1013 | 7 hours ago
Well, now. . . that presents quite a vegan quandary, doesn’t it?
Either-Patience1182 | 9 hours ago
It’s an interesting test to say the least. I want to read more on how the genetically altered the pig. so far lasting 36 hours would be good in the most desperate of pinches but a lot of things still need to be figured out. We’ll we the continued experiments in the next few years I’m sure
10ThousandMetalZones | 4 hours ago
At what point can they become bacon?
LadyZoe1 | 8 hours ago
Poor animal. I hate these “experiments in cruelty”. I believe (me, myself I) you are free to choose. Kill a genetically modified animal in order to try and prolong another animal’s life. When I die, I believe I will be reunited with all my pets who have passed. Religious people cannot begin to consider that we are murdering in order to eat. This is why, animals cannot have souls. I am not perfect, those that I failed at the time can and will rebuke me - if they so choose. If your time is up, accept it, don’t sacrifice more life to attempt to prolong yours. Why are you more important? Is their 100 percent consensus on your superior status? Or maybe narcissism?
Purple_Revolution146 | 9 hours ago
We need to have ethics in place immediately before we do unspeakable things to poor animals
Fab1e | 9 hours ago
We ar already doing unspeakable things to poor animals - on an industrial scale.
TheDesertShark | 8 hours ago
Uhhh, are you like completely unaware of the meat and dairy industries?
Noy_The_Devil | 8 hours ago
Dude..
Every second
2,400 Chickens 50 pigs and 10 cows
Die to feed humans. Every single second. They did not live happy nor long lives.
LadyZoe1 | 8 hours ago
❤️ I so agree with you. Look what we are doing to each other, our planet and now AI - Absolute Intolerance